ProQR Therapeutics NV. (Nasdaq: PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based ...

ProQR Therapeutics NV. (Nasdaq: PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology platform, today ...

Learn more about whether Moderna, Inc. or Roivant Sciences Ltd. is a better investment based on AAII's A+ Investor grades, which compare both companies' key financial metrics.

Gene editing technologies have cemented their place as a valued method in the biological toolkit used by researchers around the globe.

With more rigorous validation, the approach might be of particular interest for sites in RNA molecules where modifications are rare. (B) The overall design of DRAM, DRAM mut and Deaminase system. (F) ...

If properly validated, the approach might be of particular interest for sites where modifications are rare. (B) The overall design of DRAM, DRAM mut and Deaminase system. (D) mRNAs in DRAM-transfected ...

“指哪打哪”的RNA编辑工具：PA-rABE是如何炼成的？ PA-rABE的核心设计理念，是利用微型化的失活Cas13蛋白 (mini dCas13X) 和分裂的ADAR2去氨酶 (split ADAR2 deaminase)，并巧妙地结合了Magnets系统。Magnets系统由正磁铁 (pMag) 和负磁铁 (nMag) 组成，它们在蓝光照射下会发生二聚 ...

Airna hopes to fill that niche with technology that can recruit an enzyme known as adenosine deaminase acting on RNA, or ADAR, to modify RNA. Kris Elverum, Airna’s CEO, said the appeal of a drug ...

Co-founded by professors Thorsten Stafforst at the University of Tubingen and Jin Billy Li at Stanford University, Airna hopes to fill that niche with technology that can recruit an enzyme known as ...

发现某些胞苷脱氨酶家族 APOBEC 的脱氧胞苷脱氨酶抑制结构域（deoxycytidine deaminase inhibitor，dCDI）也可以作为 ADAR 抑制剂（ADAR inhibitor，ADI）。在RtABE ...

目前已报道有两种腺苷脱氨酶 ADAR（adenosine deaminase acting on RNA）依赖的靶向 RNA 腺苷至肌苷（A-to-I）的编辑系统。一种系统是使用外源 ADAR 与不同的定位蛋白融合表达，并通过导向 RNA 定位在转录本靶向位点诱导 RNA 编辑，但外源 ADAR 蛋白的高表达会在全转录组 ...