Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking w.

Recent cryo-electron microscopy (cryo-EM) and tomography data, also combined with crosslinking-mass spectrometry experiments, have uncovered detailed structural features of the coupling between a ...

Zhang Xinzheng at the Institute of Biophysics, Chinese Academy of Sciences, utilized cryo-electron microscopy (cryo-EM) along with their ... eEF3) to the ribosome as well as their dissociation ...

Large macromolecules and subcellular structures have proven particularly good targets for imaging with cryo-EM. Some of the most exciting advances in the field have been in determining the 3D ...

The major conformations of the ribosome and the elongation cycle ... Chinese Academy of Sciences, utilized cryo-electron microscopy (cryo-EM) along with their self-developed algorithm, GisSPA ...

Pipeline for particle picking in cryo-electron microscopy images using convolutional neural networks trained from positive and unlabeled examples. Also featuring micrograph and tomogram denoising with ...

Moreover, the study identified, for the first time, the fully rotated ribosome bound to the open form of eEF3. The researchers found that eEF3 binds to the ribosome early in translocation ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins.