Ventus Therapeutics, a clinical-stage biopharmaceutical company with two novel small-molecule programs entering Phase 2 development for immunological, inflammatory, and neurological disorders, today ...

这种结构使其能够特异性地与半胱氨酰天冬氨酸特异性蛋白酶（Caspases）结合，并在酶促反应下释放出强烈的荧光信号。 用途： 细胞凋亡研究：Z-VDVAD-AFC是研究细胞凋亡机制的重要工具。在细胞凋亡过程中，Caspases酶类扮演着至关重要的角色。Z-VDVAD-AFC能够特异性 ...

This manuscript reports fundamental discoveries on how necrotic cells contribute to organ regeneration through apoptotic signalling to produce cells with non-lethal apoptotic caspase activity that ...

Inflammatory caspases are cysteine protease zymogens whose activation following infection or cellular damage occurs within supramolecular organizing centers (SMOCs) known as inflammasomes.