This project analyzes differential gene expression (DEG) in RNA-seq data using Python & Jupyter Notebook. It applies statistical methods to identify significantly upregulated and downregulated genes ...

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

RNA sequencing refers to techniques used to determine the sequence of RNA molecules. It includes high-throughput shotgun sequencing of cDNA molecules obtained by reverse transcription from RNA ...

163.com Objectives The heterogeneity of meniscus cells and the mechanism of meniscus degeneration is not well understood. Here, single-cell RNA sequencing (scRNA-seq) was used to identify various ...

This project investigates the oxidative stress response in yeast using RNA-Seq data. The analysis focuses on understanding the differential gene expression and identifying key pathways and genes ...

Sep. 30, 2024 — The Hunga Tonga underwater volcano was one of the largest volcanic eruptions in history, and now, two years later, new research has revealed its main ... Extinct Volcanoes a ...

The central area of the spinal cord was harvested seven days after injury for the systematic analysis of global gene expression by RNA Sequencing (RNA-seq) and finally validated using qRT-PCR. Results ...

SAMseq is a nonparametric approach to differential expression in bulk sequencing, designed to be resistant to outliers (Li and Tibshirani, 2011). It uses the two-sample Wilcoxon test and Poisson ...

Here, we report a systematic transcriptional atlas to delineate molecular and cellular heterogeneity in GA using single-cell RNA sequencing (scRNA-seq). Design We performed unbiased transcriptome-wide ...

This manuscript makes a valuable contribution to the field by uncovering a molecular mechanism for miRNA intracellular retention, mediated by the interaction of PCBP2, SYNCRIP, and specific miRNA ...

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...

Sequencing refers to the techniques used to determine the primary structure of an unbranched biopolymer (DNA, RNA, protein, carbohydrate) resulting in a symbolic linear depiction of the monomeric ...