Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

modifications of the fibrin network structure resistant to the tissue plasminogen activator (tPA)-induced fibrinolysis, and the presence of non-fibrin extracellular components, such as von Willebrand ...

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In addition to increasing the grafting rate of catechol, increasing the exposure of the catechol structure can also result in superior tissue adhesion. Cui et al. (2019) attached the catechol ...