Malignant T-cell transformation after chimeric antigen receptor (CAR) T-cell therapy has been described, but the contribution of CAR integration to oncogenesis is not clear. Here we report a case ...

Weng and his team reveal that out of hundreds of animal species, amphibians, specifically frogs, have the highest number of bitter taste receptors, known as TAS2Rs. While humans have 25 TAS2Rs ...

Prolactin is a polypeptide hormone whose major biological actions are related to normal lactation and reproduction. Abnormally high prolactin levels, referred to as hyperprolactinemia, can result ...

Prolactin (PRL) and growth hormone (GH ... We also propose a hypothesis that PRL, GH and their receptors might be used by viruses as viral receptors. This may provide new insights into the ...

Here, we report the discovery of a novel, transcriptionally independent truncated isoform of ACE2, which we designate as deltaACE2 (dACE2). We demonstrate that dACE2, but not ACE2, is an ISG.

The brain contains a gland called the pituitary gland, which produces a hormone called prolactin. Prolactin is responsible for milk production, but its levels can rise due to hormonal imbalances.

Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...

In addition to the 'traditional' actions of steroid-hormone–receptor complexes — functioning in the cell nucleus as transcription factors to selectively modulate gene expression (that is ...

The healthy cells receive a low dose or no radiation. Special scans can check whether your NET has these receptors. If your NET has somatostatin receptors, doctors can use these receptors to target ...

Amongst these hormonal changes, lactogenic hormones (e.g., prolactin and its pregnancy-specific homolog, placental lactogen) are important regulators of these processes, and their receptors are ...