The introduction of all-trans retinoic acid in 1985 combined with anthracycline-based chemotherapy has revolutionized the prognosis of acute promyelocytic leukemia (APL) with current complete ...

Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia that is potentially curable with targeted therapies (such as all-trans retinoic acid and arsenic trioxide ...

The research, published in the July issue of the journal Cancer Cell, published by Cell Press, illuminates specific mechanisms involved in development of acute promyelocytic leukemia . The ...

identifies a variant in an aggressive form of acute myelogenous leukemia (AML) known as acute promyelocytic leukemia, or APL. This variant is often missed by conventional cytogenetic techniques.

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