Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia characterized by the accumulation of promyelocytes in the bone marrow and blood. Recent research has focused on improving ...

Leukemia symptoms can vary by the cancer stage and type of leukemia you have. In the early stages, leukemia symptoms like fatigue, fever, and bruising can be subtle and easily dismissed. But, as the ...

The introduction of all-trans retinoic acid in 1985 combined with anthracycline-based chemotherapy has revolutionized the prognosis of acute promyelocytic leukemia (APL) with current complete ...

The introduction of ATRA had prompted several study groups to explore the role of ATRA either as a single agent or in combination with chemotherapy. Although treatment with single-agent ATRA ...

identifies a variant in an aggressive form of acute myelogenous leukemia (AML) known as acute promyelocytic leukemia, or APL. This variant is often missed by conventional cytogenetic techniques.

The full research publication is available at: Optical Genome Mapping Reveals Complex and Cryptic Rearrangement Involving PML::RARA Fusion in Acute Promyelocytic Leukemia. Bionano is a provider of ...

Leukemia and lymphoma can have similar symptoms, including fevers, fatigue, and frequent infections. However, they do also have symptoms that make them distinct from each other. Leukemia and lymphoma ...

Acute Myeloid Leukaemia (AML) with Retinoic acid receptor-gamma (RARG) fusions have similarities to Acute Promyelocytic Leukemia (APL) but are not responsive to standard APL treatments.

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Changes in Blood Cell Production Over the Lifetime Could Impact Leukemia Outcomes Dec. 5, 2024 — The first comprehensive map of the dramatic changes that take place in the blood system over the ...