SMARCD1, a known interacting protein of TOPBP1, was also investigated in parallel. The authors report increased size and decreased number of H3K9me3-heterochromatin foci in Dux-induced 2CLCs.

Immunoglobin A (IgA) vasculitis (IgAV), formerly called the Henoch-Schönlein purpura (HSP), is a small vessel vasculitis, characterized by IgA1-dominant immune deposition at diseased vessel walls.

S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca 2+ binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little ...