SMARCD1, a known interacting protein of TOPBP1, was also investigated in parallel. The authors report increased size and decreased number of H3K9me3-heterochromatin foci in Dux-induced 2CLCs.

Among the enrolled patients, four were excluded because of failed immunostaining, and 16 patients were excluded because of incomplete follow-up data. Finally, 224 patients with GBC were included in ...

Rhabdomyosarcoma (RMS) is a soft tissue sarcoma of skeletal muscle differentiation, with a predominant occurrence in children and adolescents. One of the major challenges facing treatment success is ...

Potential Effects of Metformin on the Vitality, Invasion, and Migration of Human Vascular Smooth Muscle Cells via Downregulating lncRNA-ATB.

Background and aims Gastric intestinal metaplasia (IM) is common in the gastric epithelium of patients with chronic atrophic gastritis. CDX2 activation in IM is driven by reflux of bile acids and ...