Using Cellectis’ TALEN ® gene editing technology, we developed ‘Smart CAR T cells’ with the ability to express a CAR-inducible IL-2 variant (IL-2v) immunocytokine, potentiated by tumor-specific cues ...

近日，陆道培医院陆佩华院长作为第一作者和通讯作者，在国际血液学权威期刊 Blood（IF = 21）在线发表了题为「Nanobody-based Naturally Selected CD7-Targeted Chimeric Antigen ...

In order to demonstrate the functionality of this concept, we have constructed a large human antibody single-chain fragment (scFv) library using these principles. This library has been ...

Associated code/pipeline for the publication "AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications" ...

Informed consents were obtained from all patients. The humanized single-chain variable fragment (scFv) sequence specific for CD19 was derived from clone FMC63 as previously described (6) and the ...