为探究 SUMOylation 在前列腺癌（PCa）中的作用，研究人员发现其影响肿瘤进程，为治疗提供新靶点。 前列腺癌是男性生殖系统常见的恶性肿瘤，严重威胁男性健康。目前，雄激素剥夺疗法（ADT）是治疗局限性和晚期前列腺癌的标准方法，但大多数患者在 2 - 3 年内 ...

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes ...

Previously, the opioid analgesic drug JCT801 was reported to induce cell death via disruption of pH homeostasis in pancreatic cancer cells. Here, the authors investigate the metabolic mechanisms ...