Recent research links excessive ROS levels to cellular damage and senescence, contributing to the phenotypes associated with aging and the pathogenesis of age-related diseases. This has ushered in ...

In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...

Supplementation with exogenous KL protein protected pancreatic INS-1 cell against senescence, as indicated by downregulation of senescent markers and SA-β-gal staining. Notably, these effects were ...

ROS 2 support packages for Nova.

1Department of Obstetrics and Gynecology, Peking University Third Hospital, China 2Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing, China. 3Biobank, Peking ...

Peptides have emerged as a fascinating class of biomolecules with multifaceted roles across biological systems. Vesugen, a ...

That prevented ABCA1 from producing healthy HDL cholesterol. It also triggered inflammation and cellular senescence, a state common in aging and Alzheimer’s disease in which cells stop replicating.

This dual burden increases oxidative stress, in which reactive oxygen species (ROS) cause DNA damage, lead to genetic mutations, and promote cellular senescence, thus enhancing the vulnerability ...

腰痛已成为全球性的重大健康问题，给社会带来了沉重的经济负担，并且随着人口老龄化的加剧，这一问题愈发严重。众多研究表明，腰痛与椎间盘退变密切相关。椎间盘退变过程中，髓核细胞（nucleus pulposus cells，NPCs）和细胞外基质（extracellular matrix，ECM）会逐渐流失。细胞外基质主要由胶原纤维和蛋白聚糖（如聚集蛋白聚糖）组成，主要由髓核细胞产生并维持，其中 ...

14 Southern California Research Center for ALPD and Cirrhosis, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA The field of pancreatic stellate cell (PSC ...