Fibrosis has a key role in the progression of kidney disease and kidney failure. Here, the authors examine current options for targeting pro-fibrotic pathways, including the anti-fibrotic ...

Furthermore, bioengineering advancements have led to the development of kidney organoids—miniaturized, lab-grown kidney tissues derived from stem cells—that can model kidney development and disease, ...

Renal impairment can increase the risk of adverse drug reactions. [18] Jick [19] demonstrated a correlation between the toxicity of several cardiovascular agents and blood urea nitrogen level on ...

Feb. 19, 2025 — Clinical research suggests that combining a novel agent called navtemadlin with DNA-damaging chemotherapy for the treatment of glioblastoma, a form of brain cancer, could ...