Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

More information: Julie Thomy et al, Eukaryotic viruses encode the ribosomal protein eL40, npj Viruses (2024). DOI: 10.1038/s44298-024-00060-2 Provided by University of Hawaii at Manoa ...

particularly efficiently when ribosomal protein bS1 was present, which helps the mRNA unfold in preparation for translation inside the ribosome. The cryo-EM structures of Webster and Weixlbaumer ...

by inhibiting ribosomal protein synthesis. They also found that lariocidin binds to a unique site in the small ribosomal subunit of bacteria, which is clearly distinct from the sites of action of ...

Ribosomes are the sites in a cell in which protein synthesis takes place ... these molecules make up about half of the ribosomal mass. The remaining mass consists of a number of proteins ...

The rRNA structures also provide binding sites for ribosomal proteins, which help stabilize the ... which catalyzes the formation of peptide bonds between amino acids during protein synthesis. This ...

identifying protein degradation pathways altered explicitly in disease and employing this information to develop small molecule probes with therapeutic potential, and 3) elucidating the fundamental ...