Connective tissue diseases are a heterogeneous group of autoimmune disorders that affect any of the body's connective tissues. These disorders can be inherited or acquired, and can present with a ...

Collagen is the most abundant protein in the human body that provides structural support to connective tissues, including tendons, ligaments, cartilage, muscles, skin, and bones. Due to its rigidity ...

Patients with connective tissue diseases who experienced COVID-19-related hospitalization, severe inpatient stays, and mortality were predominantly older and men. Using glucocorticoids, rituzimab, or ...

The tunica media contains elastic lamellae and elastic fibers alternating with layers of smooth muscle cells. Proteoglycans and reticular fibers are the other components of the media. Finally, ...

The combination of tissue clearing techniques with advanced optical microscopy facilitates the achievement of three-dimensional (3D) reconstruction of macroscopic specimens at high resolution. Whole ...