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生物通
49 分钟
Topoisomerase 3b 助力 piRNA 生成,推动转座子沉默与生殖细胞发育的关键 ...
本文聚焦于双功能拓扑异构酶 Top3b 及其伙伴 TDRD3。研究发现它们主要定位于细胞质,与 PIWI 相互作用 RNA(piRNA)加工酶协作,促进 piRNA 生物合成、转座子的转录后基因沉默(PTGS)以及果蝇生殖细胞发育,为相关领域研究提供重要依据。 Topoisomerase 3b 促进 piRNA ...
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