Therefore, it is urgent to find effective and timely diagnostic markers. The objective of this study was to evaluate the diagnostic value of F-box protein 43 promoter methylation in peripheral blood ...

A urinary DNA methylation test demonstrated a high sensitivity for detecting high-grade or invasive bladder cancer, ...

Scientists are tackling society's growing obesity problem from all kinds of angles – and new research picks out a particular ...

The CRISPR-Cas9-based method allowed us to uncover a causal relationship between TSDR de-methylation and FOXP3 protein expression, with TSDR de-methylation alone being sufficient to induce FOXP3 ...

Arginine methylation is a post-translational modification that plays a significant role in regulating various cellular processes, including gene expression, signal transduction, and protein ...

at CNIO and the National Centre for Cardiovascular Research (CNIC), found that the mechanism is controlled by a mitochondrial protein, methylation-controlled J protein (MCJ). Their experiments ...

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Metabolism can change when an acetyl group attaches to lysine in a mitochondrial protein (acetylation). The addition of a methyl group to histone peptides (methylation) regulates gene expression. And ...

People with diabetes should eat as much protein as people who don't have diabetes. In a healthy diet, roughly 10% to 35% of your daily calories should come from protein. Protein itself does not have ...

However, how DNA methylation leads to gene silencing remains poorly understood. Candidates for facilitating DNA methylation-dependent gene silencing include proteins predicted to recognize methylated ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...