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铁死亡新机制!华中科技大学揭示前列腺癌治疗的“隐藏开关”
文章揭示了LTFe-LTF轴在前列腺癌中的关键作用,阐明了eRNA通过调节增强子-启动子相互作用和铁死亡来抑制肿瘤进展的机制。研究提出了一种新的治疗策略,即通过联合使用AR抑制剂和铁死亡诱导剂来克服AR靶向治疗的耐药性,为晚期前列腺癌的治疗提供了新的 ...
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