Objective: This systematic review is the first to summarize the effects of exercise training on the regulation of protein and gene expressions within the nigrostriatal glutamatergic pathway and its ...

Parkinson's disease is a progressive disorder that develops when the brain cells that produce dopamine (a chemical involved in movement) stop working or die. When this happens, symptoms like slowed ...

The GLP-1 receptor agonist exenatide failed to meet its primary outcome in a phase III trial of Parkinson's disease patients. Weekly injections of the GLP-1 receptor agonist exenatide (Byetta, ...

14, 2025 — There may be a link between hearing impairment and an increased risk of developing Parkinson's ... linked disease-related proteins and genes to identify specific cellular pathways ...

From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, scientists have been able to identify patterns of neurodegeneration and create ...

Parkinson's disease (PD) and atypical Parkinsonian syndromes are progressive heterogeneous ... positron emission tomography for quantifying nigrostriatal functions, glucose metabolism, amyloid, tau ...

Dec. 18, 2024 — Dancing lowers the depression associated with Parkinson's disease, and the benefits can be seen in multiple ways, a new study ... Nov. 19, 2024 — A recently published study ...

the test is able to identify early signs of Parkinson’s disease in individuals who have not yet shown clinical symptoms, potentially offering a new pathway for earlier intervention and improved ...

People with Parkinson's disease are more likely to develop certain types of dementia. Find out about the causes, symptoms and treatments. Parkinson’s disease is a brain disease that affects around 145 ...

npg.wustl.edu Objectives: Degeneration of nigrostriatal neurons and subsequent striatal ... and disease severity affect the physiology of dopaminergic pathways, producing altered responses to levodopa ...

Parkinson's ... disease-modification, at least in the short-term. PD is a complex neurodegenerative disorder in which many different pathophysiological processes have been identified in the ...