Here they find that glycan content (measured using the PNA lectin) of the overexpressed protein and total molecular weight, that includes amino acid weight and the glycan weight, is negatively ...

It can be applied to imaging other glycosylated RNAs using aptamers for other glycans. FUT10 and FUT11, originally annotated as α1,3-fucosyltransferases, are actually protein O ...

Department of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden ...

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China University of Chinese Academy of Sciences, Beijing 100049, China ...

“Palleon’s glycan editing therapeutic has the potential to significantly improve treatment outcomes in patients who have autoimmune diseases including lupus nephritis, with a therapy that ...

On the N-terminal, each Siglec has a V-set immunoglobulin (Ig) domain that recognizes sialic acid–containing glycans (Duan and Paulson, 2020). There are 15 human Siglecs and 9 murine Siglecs. Among ...