which are enzymes that catalyze the conversion of nucleotide sugars into deoxy and amino sugars. These sugars are vital for the biosynthesis of important biological molecules, including ...

Researchers at the University of Basel are able to test in parallel the effects of over 1,500 active substances on cell ...

Scientists have unveiled a groundbreaking method to test how thousands of active substances influence cellular metabolism ...

Analyses of qRT-PCR were performed using primer from the nucleotide sequences designed by Primer Premier 5.0 software ... Comparatively, between PP and BP, there were five up-regulated and eleven down ...

Researchers at the University of Basel are able to test in parallel the effects of over 1500 active substances on cell metabolism.

1997; Yap et al., 2017). Antimetabolite agents, including PMX, induce an imbalance in the cellular nucleotide pool and inhibit nucleic acid biosynthesis, resulting in arrested tumor cell proliferation ...

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...