Nephrolithiasis is an increasingly prevalent disorder in the elderly that is associated with multiple comorbid conditions such as hypertension, coronary artery disease, diabetes and CKD. Care of ...

unipr.it Objectives The involvement of the gut microbiota in the pathogenesis of calcium nephrolithiasis has been hypothesised since the discovery of the oxalate-degrading activity of Oxalobacter ...

Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...

In the past few decades, considerable progress has been made in understanding the complex interaction of host and pathogen, and the pathophysiology underlying both meningococcal septicaemia and ...

The evolution of a disease resulting in functional changes in your body is known as pathophysiology. To understand COPD’s pathophysiology, it’s important to understand the structure of the ...

The sodium glucose co-transporter 2 (SGLT2) functions in the proximal tubule to reabsorb the bulk of filtered glucose. SGLT2 inhibitors have been developed to promote renal glucose excretion to ...

SOUTH SAN FRANCISCO, Calif., Jan. 22, 2025 /PRNewswire/ -- Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) today announced the first patient has been enrolled in a Phase 1 study evaluating the safety ...

Dr Martin Riedel, Deutsches Herzzentrum und I. Medizinische Klinik, Technische Universität München, Lazarettstr. 36, D-80636 München, Germanym.riedel{at}dhm.mhn.de ...

1 Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China 2 The Second Affiliated Hospital, Department of Urology, Hengyang Medical School, ...

While factors such as myocardial ischaemia, worsening renal function, volume overload and chronic pulmonary disease may contribute to decompensation, the primary pathophysiology in hypertensive AHF ...

Objectives Patients with psoriatic arthritis (PsA) are at a significantly increased risk of hyperuricaemia and development of gout, and those with hyperuricaemia have been found to respond poorly to ...