CAR-T therapies have had the most success so far in targeting B-cell CD19 antigens (which is why Kymriah and Yescarta exist). However, researchers are hunting down a range of other antigens in a ...

CAR-T therapies have had the most success so far in targeting B-cell CD19 antigens (which is why Kymriah and Yescarta exist). However, researchers are hunting down a range of other antigens in a broad ...

we evaluated the specific cytotoxicity of anti-CD19 (HD37-dgRTA) and anti-CD22 (RFB4-dgRTA) ITs or their combination (Combotox) on patient-derived pre-B ALL cells maintained in vitro on a stromal ...

Additionally, CD8+ regulatory T cells, type 1 regulatory T cells (Tr1), and B regulatory cells also have a less well-defined role in the pathogenesis of SLE. Elucidation of the roles of various Treg ...

Mucosa-associated invariant T cells (MAIT ... Bacterial infection was defined as previously shown.5 B. To investigate the impact of faecal extracts on MAIT cells: stool samples were collected from 27 ...

More information: Kenji Oishi et al, MHC Class II‐Expressing Mucosal Mast Cells Promote Intestinal Mast Cell Hyperplasia in a Mouse Model of Food Allergy, Allergy (2025). DOI: 10.1111/all.16477 ...

In recent years, scientific studies have revealed that mucosal mast cells (MMCs), which are immune cells that arise from bone marrow, are excessively produced and play a key role in the severity ...

The FDA's expanded approval will allow the drug to be more accessible with insurance. Parkside Psychiatric Hospital in Tulsa has an on-site Spravato outpatient clinic that sees over 20 patients ...

State Key Laboratory of Advanced Drug Delivery and Release Systems, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China ...