A gene-edited mouse with two male parents has survived to adulthood, pushing new progress on stem cell research.

Duchenne muscular dystrophy (DMD) is a rare hereditary disease that is associated with progressive muscle wasting. The ...

2012;7(1):81-92. Homozygous R132H/R132H mice showed no serious overt phenotype, [49] which contrasts the symptoms of a patient with the corresponding mutation. However, the mice did show impaired ...

Vimentin is a type III intermediate filament (IF) protein normally expressed in cells that develop into connective tissue, ...

Repeated brain injury resulted in SOD1-ALS mice showing greater weight loss, an earlier tremor in the hind limbs, and ...

Unique mutations in the H5N1 strain enhance replication in human cells and cause severe disease in mice. The virus has spread from birds to mammals, including dairy cows, and infected humans ...

The mice also lived about 50 percent longer ... DNA edits than single-base changes -- to install a protective mutation that does not shut down protein production but rather ensures that the ...

Antibiotics are powerful, fast-acting medications designed to eradicate bacterial infections. However, in recent years, their dependability has waned as antibiotic resistant bacteria continues to ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...