METTL family members are crucial for mitochondrial function. They regulate mitochondrial ... to deliver miRNA corresponding to METTL family mRNA. More information: Jiejie He et al, METTL Family ...

Their function is to allow the translation of mitochondrial mRNA that exclusively encodes components of the oxidative phosphorylation complexes (OXPHOS). Death-associated protein 3 (DAP3), also known ...

The continued operation of faulty mitochondria could ... Insulin signaling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons, Nature Metabolism ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...