Nature11d
Mitochondrial protein import: from proteomics to functional mechanisms
Proteomic studies revealed that mitochondria contain ∼1,000 (in yeast) to 1,500 (in humans) different proteins and led to the recent identification of new mitochondrial import pathways and ...
Hosted on MSN10mon
USA Health researchers identify potential biomarker for early pancreatic cancer diagnosis
The release noted that this is the first study to show the mitochondrial protein import system’s role in promoting pancreatic cancer. “We have just begun to understand how cancer cells hijack ...
Hosted on MSN2mon
Neuron-based research model helps decode rare neurological disease
More information: Eyal Paz et al, Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50, eLife (2024). DOI: 10.7554/eLife.99914.2 ...
GEN1mon
Potential New Obesity Target Found in Mitochondrial Protein Involved in Brown Fat Thermogenesis
There are several mechanisms involved. The newly reported research has uncovered one mechanism, which they found is controlled by the mitochondrial protein MCJ. The researchers first identified ...
eLife15d
PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response
A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...