Patients with ERBB2-positive breast cancer and CNS-only metastasis are at a high risk for CNS-related death but have longer overall survival than those with concomitant extracranial metastases.

So in addition to our backbone of aromatase inhibitor treatments and tamoxifen, we are converting metastatic breast cancer into a chronic disease by addressing resistance mechanisms. So the use of ...

In this review, we summarize TAM ontogeny and polarization, and then explore how TAMs enhance tumor cell migration through the TME, thus facilitating metastasis. We also discuss how chemotherapy and ...

This review focuses on alterations in iron metabolism that enable cancer cells to meet metabolic demands required during different stages of tumorigenesis in relation to metastasis and immune response ...

But for those diagnosed with Metastatic Breast Cancer (MBC), the challenges can be even more daunting. MBC is an advanced form of breast cancer that can spread from the breast to other parts of ...

Clinical outcomes and molecular characteristics of patients with locoregional ampullary carcinoma. The effect of renin-angiotensin system inhibitors on patients with pancreatic cancer receiving ...

Prostate cancer has a tendency to spread to the bones, specifically the pelvis, upper legs, and lower spine. While those are the most common sites for prostate cancer bone metastasis, any bones in ...

9 Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China Objective Metastasis is the major cause of cancer death. However, what types of heterogenous cancer cells ...