Tumor metastasis, recurrence, and therapeutic resistance are the main reasons for the failure of clinical cancer treatment. Studies have found that ...

In a paper published in National Science Review, an international team of scientists report a coordination nanomedicine ...

CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...

The author reflects on living with HER2-positive metastatic breast cancer for over a decade, highlighting significant milestones and challenges. The eleventh year is viewed as a new beginning, ...

Lung metastases are a devastating reality for over half of cancer patients whose tumors spread beyond their initial sites. These secondary lung tumors develop in part because of unique conditions ...

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers, along with a new druggable therapeutic target to ...

They also show that PLECTIN is key for HCC invasion and metastasis. They show a correlation between PLECTIN inhibition and attenuated FAK, MAPK/ERK, and PI3K/AKT signaling. The most common primary ...

The publication reports on an interventional multi-centre Phase 1 clinical trial using the repurposed, FDA approved drug, digoxin, to treat metastatic breast cancer patients. The Parsortix ® system ...

A total of 446 patients from 136 oncology centers in Japan with HER2-positive MBC (57.6% hormone receptor positive) and no prior chemotherapy in the metastatic setting were randomly assigned to ...

Lung cancer liver metastases are tumors that form in the liver from cancer cells that have broken away from the primary cancer and spread through the blood or lymphatic system. The liver is a common ...

A metastatic breast cancer diagnosis can cause feelings of anxiety or depression. These emotions are normal and affect about half of people with metastatic breast cancer. If you’re feeling anxious or ...