decreased apoptosis and upregulation of a number of genes involved in the metastatic cascade (such as osteopontin, lysyl oxidase and vascular endothelial growth factor). Both acute and chronic ...

The Metastatic Cascade in Carcinomas: How CTC Are Formed, When & Where They Are Shed, & How Efficient They Are in Creating Metastasis Several other findings indicate the presence of tissue tropism ...

A key gene that fuels the molecular cascade driving prostate cancer bone metastasis progression may open avenues for targeted therapies. Laura is an assistant editor for The Scientist. She earned her ...

Brekken notes. He and his colleagues plan to continue studying this signaling cascade to develop new ways to monitor and combat metastasis. More information: Emily N. Arner et al, AXL-TBK1 driven ...