Metabolic syndrome (MetSyn ... Whereas linkage analysis of the genes contributing to the traits in rats and mice is straightforward, at least for those genes contributing more than a few percent ...

The enzymes change the substrate at each step in the metabolic pathway in order to get the final product at the end. There are different types of metabolic pathways – some are anabolic and some ...

non-canonical glutamine metabolic route often driven by oncogenic KRAS mutations. Inhibiting GOT2 disrupts this pathway, leading to a collapse in redox equilibrium and accumulation of reactive ...

a metabolic pathway that converts glucose into ATP, or energy, for the cell. They also discovered that during diet-induced obesity, BMAL1 works together with the hypoxia inducible factor (HIF ...

Metabolic pathways can be reversible or irreversible. Almost all pathways are reversible. If a specific enzyme or substrate isn’t available in a pathway then sometimes an end product can still ...

The safety of MTX at low doses over long periods in mice, rats and dogs has been ... way and fulfil functions as the TOR pathway, with its pleiotropic metabolic effects inhibiting cell ...