WHILE examining the histology of tuberculoid and lepromatous skin lesions of leprosy, we noted that there were many cells containing acid-fast granules in the cytoplasm, around the granulomatous ...

Depending on the harmful stimulus, different immune cell types are frequently involved, affecting the inflammation response. Granules containing pro-inflammatory substances are found inside mast ...

We hypothesize that thalamic mast cells contribute to inflammation and pain, by releasing neuro-sensitizing molecules that include histamine, IL-1β, IL-6 and TNF, as well as calcitonin-gene related ...

IT has been demonstrated that, besides heparin and histamine, mast cells contain serotonin (5-hydroxytryptamine, 5-HT) 1–3. However, serotonin-containing mast cells, having been found ...

In this study, we showed that mucosal mast cells were significantly increased in the terminal ileum, ascending colon and rectum of patients with D-IBS compared with controls. Additionally ...

Anaphylaxis is a serious, life-threatening allergic reaction. The most common anaphylactic reactions are to foods, insect stings, medications and latex. Anaphylaxis Anaphylaxis is a serious, ...

Although often believed that the pathological mechanisms operating in BP and inflammatory variant EBA are quite similar, at least in the passive-transfer disease models, mast cells may participate ...

SEE MORE Seattle’s Mast Reforestation announced today $25 million in new funding and an expansion of its operations into “wood vaulting” in which carbon that’s captured in vegetation is ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Yellow color marks genes with discordant direction of change between the ileal epithelia and full-thickness ileal segments. A) Representative images of UEA-I staining of Paneth cell granules in the ...

Feb. 10, 2025 — Influenza A virus particles strategically adapt their shape -- to become either spheres or larger filaments -- to favor their ability to infect cells depending on environmental ...

Here again the question of the endogenous protease responsible for PAR activation in the setting of IBS is crucial. Tryptase appears as an obvious candidate for activation of PAR 2 considering the ...