Our results showed an increase in the percentage of MMP-13-positive cells in PPARγ KO mice compared with control mice at 10 weeks post-OA surgery (figure 2E, F). Further, qPCR analysis on isolated ...

This valuable study reports on the critical role of ANKRD5 (ANKEF1) in sperm motility and male fertility. However, the supporting data remain incomplete. This work will be of interest to biomedical ...

用 JC - 1 染色评估线粒体膜电位（MMP），发现铀处理组细胞的绿色荧光增强，表明 MMP 明显降低，线粒体功能受到了损害。最后通过 qPCR 检测肾细胞细胞质 mtDNA 拷贝数，发现铀处理组细胞胞质中 mtDNA 基因片段 ND1 和 ND2 的丰度增加，而细胞内总 DNA 含量并未增加 ...

The MMPs of all samples were visualised by zymography and tear samples were assayed using nitrophenol acetate and an MMP-9 susceptible quenched fluorescent peptide as substrate. RESULTS The major MMPs ...

Endometriosis is a common gynecological disease, characterized by the presence of endometrial-like lesions outside the uterus. This debilitating disease causes chronic pelvic pain and infertility with ...

RT-qPCR, western blot, and immunofluorescent staining assessments showed that USH2A mutations induced apoptosis of iPSCs and ROs, and deficiency of the extracellular matrix (ECM) components.

BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

和 MDA 水平升高，GSH 和 MMP 水平降低，脂质过氧化增加 ... 能抵消 miR - 128 - 3p 抑制剂对 SLC7A11 和 GPX4 表达的抑制作用，恢复 NRF2 的表达。ChIP - qPCR 分析还表明，miR - 128 - 3p 抑制剂会显著抑制 NRF2 与 SLC7A11 启动子的结合。这一系列结果表明，PCOS 小鼠血清外泌体 ...

The quantitative mRNA expression of TNF-α, IFN-γ, IL-4, IL-10, IL-17, IL-22, IL-23, IL-27, T-bet, ROR-γT, GATA-3, MMP-1, MMP-2, and TIMP-3 genes was analyzed using SYBR Green systems. T-bet expression ...

In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...