The differentiation of human pluripotent stem cells (hPSCs) towards organoids is one of the biggest scientific advances in regenerative medicine. Kidney organoids have not only laid the groundwork for ...

Uptake transporters in the basolateral membrane and export transporters in the luminal membrane of renal tubule cells are involved in tubular secretion of their substrates (Table 1 & Figure 3).

The sodium glucose co-transporter 2 (SGLT2) functions in the proximal tubule to reabsorb the bulk of filtered glucose. SGLT2 inhibitors have been developed to promote renal glucose excretion to ...

This is a two-day course on renal pathology for Specialist Registrars and Consultants in Renal Medicine to be held on 30-31 January 2025. The course is specifically designed for nephrologists to teach ...

The novel findings are ATP6V0A1’s role in cystinosis-associated renal pathology and among other antioxidants, ATX specifically upregulated ATP6V0A1, improved autophagosome turnover or reduced ...

Dr. Xiaofan Lu presented the Abstract 442: Racial disparities in renal cell carcinoma histology and outcomes: Insights from the French Kidney Cancer Research Network (UroCCR-191). Racial disparities ...

Renal cell carcinoma (RCC) is a heterogeneous disease that represents the most common type of kidney cancer. The classification of RCC is primarily based on distinct morphological and molecular ...

6–8 It is important to understand whether this increase in SCr also indicates injury to the renal tubules and interstitium, which likely suffer the initial damage in CKDnt.9 This study aims to explore ...