Ion channels are integral membrane protein assemblies that modulate the flow of ions into and out of a cell or organelle, leading to generation of electrical signals. Opening (gating) of ion ...

Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, People’s Republic of China ...

In the mammalian central nervous system, the atypical ligand Norrin controls angiogenesis and maintenance of the blood-brain barrier and blood-retina barrier through the Wnt/β-catenin pathway. Like ...

For what concerns Cyclic nucleotide-binding domain (CNBD)-containing ion channels, the literature on this subject is vast and the authors of the present work have significantly contributed to the ...

Roles of ion channels in apoptosis and their potential in cell regulation and tumor progression were identified (Comes et al., 2015; Fraser et al., 2014; Bustin et al., 2001). The voltage-gated K +, ...

This perspective will focus on the function of resistance artery, arteriolar, and capillary endothelial cell ion channels and how they contribute to cell-cell communication involved in control of ...

and the authors recommend the use of prophylactic β-adrenergic receptor blockers in all male children who are carriers of RyR2 mutations. However, ≈30% of the patients with CPVT required an ...