Complement activation may promote atherosclerosis. Yet, data on the to which extent complement, and more specifically the alternative complement pathway, is activated in patients with carotid ...

Lepirudin has been found to be a safe and effective alternative. In this study evaluating the appropriateness of initial lepirudin doses in patients with renal insufficiency, recommended dosage ...

Physicians and other health care providers need to be aware of the importance of adjusting lepirudin bolus and maintenance doses in patients with renal insufficiency. Failure to give appropriate ...