This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

The SCN clockwork is a self-sustaining transcriptional-translational feedback loop (TTFL) that in turn co-ordinates the expression of clock-controlled genes (CCGs) directing circadian programmes of ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

But Gounder had an idea: Perhaps Wolff's genes could point them in the right direction. Dr. Mrinal Gounder, a sarcoma medical oncologist at Memorial Sloan Kettering Cancer Center (MSK) in New York ...

Significant gene variants were found in the loci DRD2, FURIN, and CYP7B1, which play a part in neuroinflammation, neurosteroid synthesis, and synaptic function.

While genes cannot be modified, knowledge of genetic risks can help people make lifestyle changes to lower their risk.” The absence of population-specific genomic data has often limited the success of ...

The first human trial of insulin-producing cells that have been gene-edited to evade immune attack is a success so far. The cells have survived and produced insulin for a month after being ...

Scientists led by a team at Columbia University have trained a model to predict how the genes inside a cell will drive its behavior, which could be a powerful tool with the potential to broaden ...

9 identified the direct epigenetic effects of two common byproducts of fiber digestion and found that some of the alterations in gene expression had anti-cancer actions. When we eat fiber ...

They’ll check the fetus for mutations in the NOD2 gene. Finding a mutation in the gene doesn’t mean a diagnosis of Crohn’s disease. It only indicates an increased risk for developing the ...