Although limited in quantity, the retained histones in sperm bearing abundant modifications are still essential in male reproduction (Liu et al., 2019), embryo development (Hammoud et al., 2009; ...

Histone post-translational modifications are covalent modifications of histones by phosphorylation on serine or threonine residues, methylation on lysine or arginine, acetylation and deacetylation ...

Despite the growing recognition of histone modifications in tumor progression, their role in LGG remains poorly understood. This study aimed to develop a histone modification-based risk signature and ...

Recently, menin was also shown to be involved in methylation of the fourth lysine (K) residue of the histone H3 (H3K4 methylation). This modification is linked to activation of transcription ...

Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Ph.D. Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University and National Health Research Institutes, Taipei 110, Taiwan International Master Program in ...

Whether it’s job loss, illness, or divorce — if you’re having trouble paying your mortgage, a loan modification could be your best solution. If you qualify and can handle the new terms that ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

If you’re not afraid of a little NSFW language, and are in the mood to hear a Gen Z success story, then sit back and enjoy today’s tale (courtesy of Reddit) of how one high school dropout went ...