Objective IgG4-related disease (IgG4-RD) is a heterogeneous, multiorgan condition of unclear aetiology that can cause organ failure. Difficulty recognising IgG4-RD contributes to diagnostic delays. We ...

Objectives Hypocomplementaemia is common in patients with IgG4-related disease (IgG4-RD). We aimed to determine the IgG4-RD features associated with hypocomplementaemia and investigate mechanisms of ...

In 2008 and 2011 large outbreaks were also described in China (490 000 cases) and Vietnam (110 000 cases).2 The recent Cambodian outbreak further demonstrates the emergence and spread of serious EV71 ...

RFK Jr., who trained as an environmental lawyer, announced his candidacy for the 2024 U.S. presidential election, initially as a Democrat before switching to an Independent bid. However, after ...

In 2022, more than 941,600 Americans died from cardiovascular disease. Heart disease remains ... cardiovascular-related deaths have begun plateauing after ticking upward during the COVID-19 ...

This is partly due to the fact that the complex pathophysiology of Alzheimer's disease is not yet completely understood. Recently, Golgi apparatus is found to play an important role in Alzheimer's ...

"It was the scene of a state-organized crime," said Heubner. "And the crime was setting up an industrial apparatus to kill people." It took decades before a wider process of confronting the ...

Nature Research Intelligence Topics enable transformational understanding and discovery in research by categorising any document into meaningful, accessible topics. Read this blog to understand ...

Mitochondria play a crucial role in modulating immune responses by influencing cell signaling pathways, making them a potential target for treating inflammatory diseases.

Age-related assumptions about different types of diabetes mellitus increase the risk of misdiagnosis. Type 2 diabetes has a number of symptoms that may be mistaken for other disorders. A wide range of ...

Golgi Protein 73 (GP73) is a Golgi-resident protein that is ... GP73 can disrupt the homeostasis of the immune microenvironment by regulating inflammation-related signaling pathways in tissue and ...