Permanent change in DNA leading to the loss of function of a gene, caused by a manipulation of the organism's DNA in a laboratory followed by breeding to produce a population of organisms that are ...

Both gene knockout and knock-in models are powerful tools widely used in biomedical research to gain important insights into ...

Gene knockout approaches completely ablate gene expression at the DNA level. 3 Researchers can accomplish this by using genome editing tools, such as zinc finger nucleases (ZFN), transcription ...

Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...

Synthego, a leading genome engineering solutions company, today announced the launch of the Gene Knockout Kit v2. This is the only product that leverages a novel ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

EditCo Bio, a leader in cutting-edge genetic engineering and cellular model solutions, today announced the launch of XDel Knockout Cells, an innovative product designed to revolutionize the field of ...