C&EN24 天
Design of ROS-Triggered Sesquiterpene Lactone SC Prodrugs as TrxR1 Covalent Inhibitors for ...
Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province; Engineering Research Center of Natural Medicine Active Molecule Research & Development ...
C&EN27 天
Synergistic Enhancement of Ferroptosis via Mitochondrial Accumulation and Photodynamic ...
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China CAS Key Laboratory for ...
Frontiers1 个月
Prodrug-based bispecific antibodies for cancer therapy: advances and future directions
To increase tumor selectivity while mitigating off-target effects in normal tissues, the concept of prodrug-based bispecific antibodies has emerged. This review delineates the various mechanisms ...
Lawrence Journal-World8 年
‘It’s the impact you have on people’s lives’: Retiring KU professor invented widely ...
Stella has specialized in prodrugs, which involve developing better ... It’s also used to treat chronic hepatitis B. • Fosphenytoin (the brand name is Cerebyx), a water-soluble form of ...