高度近视在全球的患病率呈上升趋势,已成为严峻的健康挑战。高度近视性白内障作为高度近视最常见的并发症,发病年龄比年龄相关性白内障更早,严重影响患者工作期间的生活质量。由于晶状体核通常较硬,HMC 的手术干预难度较大,因此深入了解其发病机制对开发潜在治疗方法至关重要。
Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...
Department of Chemistry, Chemistry of Life Processes Institute, and Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois 60208, United States Department of Chemistry, ...
Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated ...
A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...
Diseases spread through saliva include mononucleosis, strep throat, rotavirus, and even tooth decay. Many diseases can be spread through saliva alone, including viral and bacterial infections. Our ...
Recent research suggests that one key player in reducing the risk and progression of Alzheimer’s could be aerobic exercise.
High blood pressure affects multiple organs. Not only can hypertension add stress to the heart and damage arteries, leading to heart disease, but it also can cause strokes and kidney disease as ...
Alzheimer's disease could be slowed by aerobic exercise ... "Iron overload in the oligodendrocytes is an inducer of ferroptosis in aged brains," the researchers wrote. The researchers found ...
Regular aerobic exercise could significantly reduce disease markers associated with ... oligodendrocytes ferroptosis, and inflammaging in the hippocampal formation of aged rats submitted to ...