Exosome Component 4 (EXOSC4) is involved in RNA degradation ... Knockdown of EXOSC4 can inhibit the proliferation, migration, and invasion ability of EOC by suppressing the Wnt pathway. EXOSC4 is ...

Exosomes, nano-sized extracellular vesicles secreted by all cells, are a fundamental part of the human body’s internal communication machinery, safely and efficiently transporting proteins and ...

Secreted vesicles known as exosomes were first discovered nearly 30 years ago. But, considered little more than garbage cans whose job was to discard unwanted cellular components, these small vesicles ...

Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, ...

Exosomes offer a number of advantages as drug ... activating downstream pathways necessary for the protein synthesis underlying axonal growth and regeneration (Fig. 2). ExoPTEN has been tested ...

In the article “Neuronal innervation regulates the secretion of neurotrophic myokines and exosomes from skeletal muscle,” Huang et al. demonstrate that innervated skeletal muscle produces neurotrophic ...

The Gould Laboratory studies vesicles, known as exosomes and microvesicles (EMVs), that can be taken up by neighboring cells, completing a pathway of intercellular vesicle traffic. Our laboratory ...

Furthermore, exosomes are naturally occurring cell-derived nanovesicles that can serve as ... via trigeminal and olfactory nerves via axonal or endocytic routes and intra- or extra-neuronal pathways, ...

M1 Macrophage-Derived Exosomes: These vesicles exhibit anti-tumor properties by delivering miRNAs that inhibit oncogenic pathways in HCC cells. Cancer-Associated Fibroblast (CAF)-Derived Exosomes ...

The micro-puncturing from these treatments create pathways in the skin; the specialist then applies the exosomes through a gel on the skin, and the exosomes can reach stagnant cells and ...

US biotech PureTech Health has signed a potential billion-dollar deal with Roche based around its exosome technology that allows for oral administration of complex payloads – in this case ...