While much of the physical brain damage occurs instantly - called the primary stage of injury - additional brain damage can result from the destructive chemical processes that arise in the body ...
(THE CONVERSATION) Traumatic brain injury is a leading cause of death and disability in the world. Blunt force trauma to the brain, often from a bad fall or traffic accident, accounts for the deaths ...
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Objectives Comorbidity in traumatic brain injury (TBI) has been recognised to alter the clinical course of patients and influence short-term and long-term outcomes. We synthesised the evidence on the ...
The following decades provided critical insights into the molecular underpinnings of the excitotoxic process. The ionic dependence of excitotoxicity and the crucial role played by the overactivation ...
In the present study, we investigated the impact of PAO inhibition in limiting retinal neurodegeneration in a model of NMDA (N-Methyl-D-aspartate)-induced excitotoxicity. Adult mice (8–10 weeks old) ...