CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology; CAS Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, China Tsinghua ...
This valuable study on Pseudomonas subverting host immunity identifies a new immune evasion strategy. There is solid evidence for the cleavage of VgrG2B by Caspase 11 and the generation of fragments ...
MLE-12 mouse lung epithelial cells (#JY106, Jingyuan Biotechnology ... cleaved caspase-1, IL-1β, Gasdermin D (1:200; GSDMD, #AF4012, Affinity Biosciences), cluster of differentiation 86 (1:400; CD86, ...
敲除 pir-hsa-216911 导致细胞焦亡活性增加,从而激活了 caspase-1 和 GSDMD。进一步分析表明,pir-hsa-216911 通过抑制与 HCC 细胞焦亡相关的关键基因 TLR4 ...