We each get two copies of every gene - one copy from each of our parents. But what happens when one of these genes has been "turned off", or imprinted, and the remaining gene is defective?

Acquisition of the constitutively active Janus kinase 2 (JAK2)V617F mutation occurs in almost all patients with polycythaemia vera (PV) and in a significant number of patients with essential ...

All had been referred to us by their physicians, after treatment with several standard medications for relief of this disorder ... The total peripheral blood granulocytes per cubic millimeter ...