Researchers from the Huntington's Disease Center, UCL Queen Square Institute of Neurology, and UK DRI at UCL have taken major ...

"We are puzzled why stopping a subset of CAG repeats from expanding in Msh3- or Pms1-deficient HD mice could lead to a ...

"We are puzzled why stopping a subset of CAG repeats from expanding in Msh3- or Pms1-deficient HD mice could lead to a benefit in all striatal neurons," said Nan Wang, a co-first author in the study.

Using CRISPR technology, scientists uncovered genes that control C-A-G genetic stumbles in Huntington's disease ...

Both Tabrizi and Yang think that knocking down MSH3 could stave off HD pathology. Tabrizi noted that MSH3 also modifies other run-on repeats, including those causing fragile X syndrome, myotonic ...

内容简介罗氏公司（Roche）推出了一种全新的高通量测序技术，名字叫“SPX”技术，是“Expansion Technology”的缩写。通过给4种碱基加上长的链子，链子上带特定序列信号，再在 DNA ...

Less than a month after researchers unveiled that a “ticking DNA clock” is behind Huntington’s disease (HD), scientists have ...

Scientists have developed a breakthrough method to track diet using stool metagenomic data, offering an objective alternative ...