吸烟会通过损伤机体DNA来引起癌症，目前科学家们对 肺癌 的测序工作发现了与暴露烟草烟雾致癌物苯并 [a]芘 (benzo [a]pyrene)有关的突变特征，苯并 [a]芘能在细胞中代谢成为苯并 [a]芘二醇环氧化物 (BPDE,benzo ...

Cancer arises when your cells grow uncontrollably and refuse to die when they should. Normally, your body is equipped with ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

The study from The Hebrew University of Jerusalem, led by Prof. Sheera Adar and her graduate student Elisheva Heilbrun-Katz ...

Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped these damages has revealed that the way ...

The study, published in Nucleic Acids Research, focused on benzo (a)pyrene, a toxic chemical in cigarette smoke, which binds to DNA when processed by the body, and disrupts its normal function and ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

CMRI researchers discovered that DNA repair pathways control how cancer cells die after radiotherapy. Blocking a key repair ...

A UCLA study reveals that DNA repair genes play a crucial role in Huntington's disease, driving neuronal damage.

In addition, there are a handful of syndromes with an etiological link to DNA damage and repair that exhibit symptoms of accelerated aging but have no striking neurological symptoms. Such ...

Researchers are now working to better understand a process that can help repair that damage. Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals.