Cytoreductive nephrectomy (CN) of the primary tumor ... substantially from CN in the era of targeted therapy and the indication for surgery should be 'personalized'. To obtain benefit from CN ...

The strongest evidence for a survival benefit following CN stems from the two randomized Phase III studies investigating nephrectomy followed by IFN-α versus IFN-α alone. A combined analysis of ...

Deferred cytoreductive nephrectomy is associated with better survival compared with upfront surgery, including among fit patients receiving immunotherapy. Deferred cytoreductive nephrectomy (CN ...

Cytoreductive nephrectomy was then offered to the patient, who opted to undergo this procedure via a laparoscopic approach. Figure 2: Imaging of the patient's kidney after administration of sunitinib.