The coexistence of transthyretin cardiac amyloidosis (ATTR‐CA) and aortic stenosis (AS) is increasingly recognized, but the clinical consequences are unclear. We aimed to characterize clinical ...
Hereditary transthyretin (hATTR) amyloidosis is a rare progressive disease that is passed from parent to child. It is caused by a mutant form of the transthyretin (TTR) protein that can damage vital ...
Alzheimer’s disease is a dominant form of dementia, representing 60 to 70 percent of cases. Recent approvals by the Food and Drug Administration have focused on medications that shrink the sticky ...
Multiple myeloma and AL amyloidosis are conditions linked to plasma cells in the bone marrow. Multiple myeloma (MM) is a cancer affecting the plasma cells, which are mostly in the bone marrow.
2000; Selkoe and Podlisny, 2002; Goedert and Spillantini, 2006). Its pathophysiology involves extracellular amyloid plaque, in which the primary protein constituents aggregated Aβ (Querfurth and ...
Data are expressed as mean±SD, median (interquartile range) or n (%). AL indicates abnormalities between light chain; BSA, body surface area; DBP, diastolic blood pressure; eGFR, estimated glomerular ...